Inhaled corticosteroids and adrenal insufficiency

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Inhaled corticosteroids and adrenal insufficiency.

Inhaled steroids are safe at normal doses, but beware very high doses, especially of fluticasone

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Inhaled Corticosteroids and Secondary Adrenal Insufficiency

Inhaled corticosteroids (ICS) have been used as first line treatment of asthma for many decades. ICS are a form of exogenous glucocorticosteroids that can suppress the endogenous production of glucocorticosteroids, a condition known as adrenal suppression (AS). As a result, cessation, decreasing the dose or changing the type of ICS may trigger features of adrenal insufficiency (AI). AI may caus...

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Getting risks right on inhaled corticosteroids and adrenal insufficiency.

As Thomas Addison observed in his famous monograph written in 1855, the adrenal glands are ‘‘objects of deep interest’’ and so they remain [1]. In the monograph he described several patients who presented with generalised weakness and in whom abnormalities of the adrenal glands were found at post mortem. Addison had discovered primary hypoadrenalism, the disease that would later take his name. ...

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Oral and inhaled corticosteroids and adrenal insufficiency: a case-control study.

BACKGROUND Adrenal insufficiency, a well recognised complication of treatment with oral corticosteroids, has been described in association with inhaled corticosteroid use in over 60 case reports. The risk of adrenal insufficiency in people prescribed an oral or inhaled corticosteroid in the general population is not known. A study was undertaken to quantify the association between adrenal insuf...

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EPIDEMIOLOGY Oral and inhaled corticosteroids and adrenal insufficiency: a case-control study

Background: Adrenal insufficiency, a well recognised complication of treatment with oral corticosteroids, has been described in association with inhaled corticosteroid use in over 60 case reports. The risk of adrenal insufficiency in people prescribed an oral or inhaled corticosteroid in the general population is not known. A study was undertaken to quantify the association between adrenal insu...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 2002

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.87.6.455